Graeme Henderson

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
Area:
Opioid receptor regulation
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"Graeme Henderson"
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Elizabeth Seward grad student University of Bristol (Physiology Academic Tree)
Mark Connor post-doc 1993-1996 University of Bristol
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Publications

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Hancox JC, Wang Y, Copeland CS, et al. (2024) Nitazene opioids and the heart: Identification of a cardiac ion channel target for illicit nitazene opioids. Journal of Molecular and Cellular Cardiology Plus. 10: 100118
Alhosan N, Cavallo D, Santiago M, et al. (2024) Slow dissociation kinetics of fentanyls and nitazenes correlates with reduced sensitivity to naloxone reversal at the μ-opioid receptor. British Journal of Pharmacology
Ramos-Gonzalez N, Groom S, Sutcliffe KJ, et al. (2023) Carfentanil is a β-arrestin-biased agonist at the μ opioid receptor. British Journal of Pharmacology
Kelly E, Conibear A, Henderson G. (2022) Biased Agonism: Lessons from Studies of Opioid Receptor Agonists. Annual Review of Pharmacology and Toxicology
Groom S, Blum NK, Conibear AE, et al. (2020) A novel G protein-biased agonist at the μ opioid receptor induces substantial receptor desensitization through G protein-coupled receptor kinase. British Journal of Pharmacology
Gillis A, Kliewer A, Kelly E, et al. (2020) Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor. Trends in Pharmacological Sciences
Kliewer A, Gillis A, Hill R, et al. (2020) Morphine-induced respiratory depression is independent of ß-arrestin2 signalling. British Journal of Pharmacology
Hill R, Roberts J, Maclachlan J, et al. (2019) Prolonged ethanol administration prevents the development of tolerance to morphine-induced respiratory depression. Drug and Alcohol Dependence. 205: 107674
Degenhardt L, Grebely J, Stone J, et al. (2019) Global patterns of opioid use and dependence: harms to populations, interventions, and future action. Lancet (London, England). 394: 1560-1579
Conibear AE, Asghar J, Hill R, et al. (2019) A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain. The Journal of Pharmacology and Experimental Therapeutics
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