Steffany A. Bennett, Ph.D

Affiliations: 
Biochemistry, Microbiology and Immunology University of Ottawa, Ottawa, ON, Canada 
Area:
regulation of neural stem cell fate by connexin proteins, glycerophospholipid neuromodulators
Website:
http://137.122.232.177/index.html
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"Steffany Bennett"
Bio:

Dr. Steffany Bennett is a lipid biochemist, systems biologist, and neurobiologist working to both block the pathological changes in brain lipid metabolism that precipitate Alzheimer's Disease and to promote functional neural cell replacement by altering cell-cell (connexin-mediated) communication. She received her Ph.D. from the University of Ottawa in 1995 and completed post-doctoral training at the W. Alton Jones Cell Science Centre, USA (Lab of Dr. Martin Tenniswood) in collaboration with (Dr. Bruce Pappas, Carleton University) and Harvard Medical School, USA (Lab of Dr. David Paul) in collaboration with Dr. Gerry Melino (University of Tor Vergata, Italy). In 1999, she was recruited to the University of Ottawa and is currently a Professor and University Research Chair in Neurolipidomics in the Department of Biochemistry, Microbiology, and Immunology, University of Ottawa. She is also the Director of the Neural Regeneration Laboratory, Associate Director (Education) of the Ottawa Institute of Systems Biology, and the Director of the STIHR/CIHR Training Program in Neurodegenerative Lipidomics.
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Mean distance: 14.51 (cluster 6)
 
SNBCP
Cross-listing: Chemistry Tree

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Publications

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Pileggi CA, Blondin DP, Hooks BG, et al. (2022) Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity. Ebiomedicine. 104192
Gouveia A, Hsu K, Niibori Y, et al. (2016) The aPKC-CBP Pathway Regulates Adult Hippocampal Neurogenesis in an Age-Dependent Manner. Stem Cell Reports
Swayne LA, Bennett SA. (2016) Connexins and pannexins in neuronal development and adult neurogenesis. Bmc Cell Biology. 17: 10
Kennedy MA, Kabbani N, Lambert JP, et al. (2011) Srf1 is a novel regulator of phospholipase D activity and is essential to buffer the toxic effects of C16:0 platelet activating factor. Plos Genetics. 7: e1001299
Redensek A, Rathore KI, Berard JL, et al. (2011) Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury. Glia. 59: 603-14
Bou Khalil M, Hou W, Zhou H, et al. (2010) Lipidomics era: accomplishments and challenges. Mass Spectrometry Reviews. 29: 877-929
Swayne LA, Sorbara CD, Bennett SA. (2010) Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. The Journal of Biological Chemistry. 285: 24977-86
Ryan SD, Whitehead SN, Swayne LA, et al. (2009) Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism. Proceedings of the National Academy of Sciences of the United States of America. 106: 20936-41
Kennedy KA, Porter T, Mehta V, et al. (2009) Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative beta-catenin. Bmc Biology. 7: 67
Ryan SD, Harris CS, Carswell CL, et al. (2008) Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons. Journal of Lipid Research. 49: 2250-8
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