David Friel

Case Western Reserve University, Cleveland Heights, OH, United States 
Calcium Regulation
"David Friel"
Mean distance: 13.47 (cluster 11)


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Michael A Patterson research assistant 2000-2004 Case Western
Saak V. Ovsepian post-doc 2005-2007 Rutgers
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Friel D. (2013) The cell boundary theorem: a simple law of the control of cytosolic calcium concentration. The Journal of Physiological Sciences : Jps. 63: 159
Friel DD. (2013) Impact of a loss-of-function P/Q type Ca2+ channel mutation on excitatory synaptic control of cerebellar purkinje neurons Modulation of Presynaptic Calcium Channels. 2147483647: 243-261
Saftenku EE, Friel DD. (2012) Combined computational and experimental approaches to understanding the Ca(2+) regulatory network in neurons. Advances in Experimental Medicine and Biology. 740: 569-601
Ovsepian SV, Friel DD. (2012) Enhanced synaptic inhibition disrupts the efferent code of cerebellar Purkinje neurons in leaner Cav2.1 Ca 2+ channel mutant mice. Cerebellum (London, England). 11: 666-80
Frey MM, Hutterli MA, Chen G, et al. (2009) Contrasting atmospheric boundary layer chemistry of methylhydroperoxide (CH3OOH) and hydrogen peroxide (H2O2) above polar snow Atmospheric Chemistry and Physics. 9: 3261-3276
Liu S, Friel DD. (2008) Impact of the leaner P/Q-type Ca2+ channel mutation on excitatory synaptic transmission in cerebellar Purkinje cells. The Journal of Physiology. 586: 4501-15
Friel DK, Snapper ML, Hoveyda AH. (2008) Aluminum-catalyzed asymmetric alkylations of pyridyl-substituted alkynyl ketones with dialkylzinc reagents. Journal of the American Chemical Society. 130: 9942-51
Ovsepian SV, Friel DD. (2008) The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts. The European Journal of Neuroscience. 27: 93-103
Friel DD, Chiel HJ. (2008) Calcium dynamics: analyzing the Ca2+ regulatory network in intact cells. Trends in Neurosciences. 31: 8-19
Patterson M, Sneyd J, Friel DD. (2007) Depolarization-induced calcium responses in sympathetic neurons: relative contributions from Ca2+ entry, extrusion, ER/mitochondrial Ca2+ uptake and release, and Ca2+ buffering. The Journal of General Physiology. 129: 29-56
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