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O. Hayes Griffith

Affiliations: 
Chemistry University of Oregon, Eugene, OR, United States 
Area:
membrane enzymes
Website:
http://chemistry.uoregon.edu/fac.html?griffith
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"O. Hayes Griffith"
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Parents

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Harden M. McConnell grad student 1964 Caltech
 (Electron spin resonance of several molecules in the solid state)

Children

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Alan  S. Waggoner grad student 1969 University of Oregon
M. S. Shashidhar post-doc 1987-1991 University of Oregon

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Publications

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Birrell GB, Zaikova TO, Rukavishnikov AV, et al. (2003) Allosteric interactions within subsites of a monomeric enzyme: kinetics of fluorogenic substrates of PI-specific phospholipase C. Biophysical Journal. 84: 3264-75
Ryan M, Zaikova TO, Keana JF, et al. (2002) Listeria monocytogenes phosphatidylinositol-specific phospholipase C: activation and allostery. Biophysical Chemistry. 101: 347-58
Griffith OH, Ryan M. (1999) Bacterial phosphatidylinositol-specific phospholipase C: structure, function, and interaction with lipids. Biochimica Et Biophysica Acta. 1441: 237-54
Rukavishnikov AV, Zaikova TO, Birrell GB, et al. (1999) Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase C. Bioorganic & Medicinal Chemistry Letters. 9: 1133-6
Rukavishnikov AV, Smith MP, Birrell GB, et al. (1998) Synthesis of a new fluorogenic substrate for the assay of phosphoinositide-specific phospholipase C Tetrahedron Letters. 39: 6637-6640
Rukavishnikov AV, Zaikova TO, Griffith OH, et al. (1997) Improved synthesis of myo-inositol 1-(4-nitrophenyl hydrogen phosphate), a chromogenic substrate for phosphatidylinositol-specific phospholipase C. Chemistry and Physics of Lipids. 89: 153-7
Liu T, Ryan M, Dahlquist FW, et al. (1997) Determination of pKa values of the histidine side chains of phosphatidylinositol-specific phospholipase C from Bacillus cereus by NMR spectroscopy and site-directed mutagenesis. Protein Science : a Publication of the Protein Society. 6: 1937-44
Rukavishnikov AV, Ryan M, Griffith OH, et al. (1997) A chromogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase C Bioorganic and Medicinal Chemistry Letters. 7: 1239-1242
Griffith OH, Gaffney BJ, Kwiram AL. (1993) Harden M. McConnell: a Celebration of His Scientific Achievements The Journal of Physical Chemistry. 97: 2805-2822
Shashidhar MS, Volwerk JJ, Griffith OH, et al. (1991) A chromogenic substrate for phosphatidylinositol-specific phospholipase C: 4-nitrophenyl myo-inositol-1-phosphate. Chemistry and Physics of Lipids. 60: 101-10
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