Siegfried Hekimi

Affiliations: 
McGill University, Montreal, QC, Canada 
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"Siegfried Hekimi"
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Branicky R, Wang Y, Khaki A, et al. (2022) Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expression. Science Advances. 8: eadc9851
Wang Y, Gumus E, Hekimi S. (2022) A novel mutation causing primarily neuromuscular pathology and its treatment options. Molecular Genetics and Metabolism Reports. 31: 100877
Wang Y, Hekimi S. (2020) Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations. Redox Biology. 36: 101680
Kramer-Drauberg M, Liu JL, Desjardins D, et al. (2020) ROS regulation of RAS and vulva development in Caenorhabditis elegans. Plos Genetics. 16: e1008838
Krabbendam IE, Honrath B, Dilberger B, et al. (2020) SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans. Cell Death & Disease. 11: 263
Wang Y, Hekimi S. (2019) The Complexity of Making Ubiquinone. Trends in Endocrinology and Metabolism: Tem
Wang Y, Branicky R, Noë A, et al. (2018) Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling. The Journal of Cell Biology
Hughes BG, Harrison PM, Hekimi S. (2017) Estimating the occurrence of primary ubiquinone deficiency by analysis of large-scale sequencing data. Scientific Reports. 7: 17744
Wang Y, Smith C, Parboosingh JS, et al. (2017) Pathogenicity of two COQ7 mutations and responses to 2,4-dihydroxybenzoate bypass treatment. Journal of Cellular and Molecular Medicine
Liu JL, Yee C, Wang Y, et al. (2017) A single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1. Scientific Reports. 7: 859
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