Joong Sup Shim
Affiliations: | University of Macau |
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Publications
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| Tao S, Yang EJ, Zong G, et al. (2023) ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones. International Journal of Biological Sciences. 19: 4020-4035 |
| Ren G, Yang EJ, Tao S, et al. (2023) MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism. International Journal of Biological Sciences. 19: 3544-3557 |
| Wang X, Huang J, Liu F, et al. (2023) Aurora A kinase inhibition elevates PD-L1 expression and compromises its anti-tumor efficacy. The Journal of Clinical Investigation |
| Shi C, Tao S, Ren G, et al. (2022) Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation. Oncogene |
| Zhang L, Chen C, Fu J, et al. (2021) Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa. Elife. 10 |
| Shi C, Yang EJ, Liu Y, et al. (2020) Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression. Oncogene |
| Hwang HY, Shim JS, Kim D, et al. (2020) Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein. Autophagy |
| Liu Y, Yang EJ, Shi C, et al. (2020) Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT. International Journal of Biological Sciences. 16: 1774-1784 |
| Zhang B, Lyu J, Yang EJ, et al. (2020) Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells. Acta Pharmaceutica Sinica. B. 10: 615-627 |
| Lyu J, Yang EJ, Shim JS. (2019) Cholesterol Trafficking: An Emerging Therapeutic Target for Angiogenesis and Cancer. Cells. 8 |