David Luke Fischer, M.D., Ph.D.

2006-2010 Radiology, Neurology Michigan State University, East Lansing, MI 
 2010-2018 Translational Science and Molecular Medicine Michigan State University, East Lansing, MI 
 2018- Neurology University of Alabama, Birmingham, Birmingham, AL, United States 
Parkinson's disease, deep brain stimulation, brain-derived neurotrophic factor
"D. Luke Fischer"

D. Luke Fischer is a neuroscientist specializing in Parkinson's disease research. He graduated Phi Beta Kappa from Michigan State University with degrees in Philosophy and Biochemistry & Molecular Biology, and he remained there to complete his PhD in Neuroscience in the laboratory of Dr. Caryl E. Sortwell as part of a dual-MD/PhD program. As a trainee in the NINDS Morris K. Udall Center of Excellence for Parkinson's Disease Research at Michigan State University, his focus was on the use of deep brain stimulation in rodent models of Parkinson's disease to investigate its potential as a neuroprotective therapy. He remained in her laboratory as a postdoctoral fellow to examine the impact of common genetic variants on clinical outcomes for developing precision medicine approaches for treating patients with Parkinson's disease. Luke is currently in the neurology residency program at the University of Alabama at Birmingham.

Mean distance: 18.69 (cluster 19)


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Kevin L. Berger research assistant 2007-2010 Michigan State
Andrea Cathryn Bozoki research assistant 2007-2010 Michigan State
Caryl E. Sortwell grad student 2010-2015 Michigan State
Caryl E. Sortwell post-doc 2015-2016 Michigan State


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Timothy  J. Collier collaborator 2010-2018 Michigan State
Jack W. Lipton collaborator 2011-2018 Michigan State
Fredric P. Manfredsson collaborator 2012-2018 Michigan State
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Fischer DL, Gombash SE, Kemp CJ, et al. (2016) Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease. Methods in Molecular Biology (Clifton, N.J.). 1382: 367-82
Fischer DL, Collier TJ, Cole-Strauss A, et al. (2015) High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine. Plos One. 10: e0133957
Gombash SE, Manfredsson FP, Mandel RJ, et al. (2014) Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Therapy. 21: 682-93
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