Sean M. O'Shea, Ph.D.

2000 University of Chicago, Chicago, IL 
Neuroscience Biology, Molecular Biology, Biochemistry
"Sean O'Shea"
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Neil L. Harrison grad student 2000 Chicago
 (Modulation and gating of the GABA(A) receptor: The role of the alpha subunit.)
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O'Shea SM, Williams CA, Jenkins A. (2009) Inverse effects on gating and modulation caused by a mutation in the M2-M3 Linker of the GABA(A) receptor gamma subunit. Molecular Pharmacology. 76: 641-51
O'Shea SM, Becker L, Weiher H, et al. (2004) Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2322-7
Kung AY, Rick C, O'Shea S, et al. (2001) Expression of glycine receptors in rat sensory neurons vs. HEK293 cells yields different functional properties. Neuroscience Letters. 309: 202-6
O'Shea SM, Harrison NL. (2000) Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor alpha 2 subunit define agonist efficacy and potency. The Journal of Biological Chemistry. 275: 22764-8
O'Shea SM, Wong LC, Harrison NL. (2000) Propofol increases agonist efficacy at the GABA(A) receptor. Brain Research. 852: 344-8
Krasowski MD, O'Shea SM, Rick CE, et al. (1997) Alpha subunit isoform influences GABA(A) receptor modulation by propofol. Neuropharmacology. 36: 941-9
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