Goldis Malek, Ph.D.

Affiliations: 
2002 University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Ophthalmology, Anatomy Biology
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Christine A. Curcio grad student 2002 UAB
 (Investigation of lipid-related components in sub-retinal pigment epithelial deposits of normal and age-related maculopathy eyes.)
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Publications

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Espinosa-Heidmann DG, Malek G, Mettu PS, et al. (2013) Bone marrow transplantation transfers age-related susceptibility to neovascular remodeling in murine laser-induced choroidal neovascularization. Investigative Ophthalmology & Visual Science. 54: 7439-49
Hu P, Herrmann R, Bednar A, et al. (2013) Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology. Proceedings of the National Academy of Sciences of the United States of America. 110: E4069-78
Malek G, Dwyer M, McDonnell D. (2012) Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD Advances in Experimental Medicine and Biology. 723: 51-59
Dwyer MA, Kazmin D, Hu P, et al. (2011) Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration. Molecular Endocrinology (Baltimore, Md.). 25: 360-72
Anderson DH, Radeke MJ, Gallo NB, et al. (2010) The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Progress in Retinal and Eye Research. 29: 95-112
Zweifel SA, Spaide RF, Curcio CA, et al. (2010) Reticular pseudodrusen are subretinal drusenoid deposits. Ophthalmology. 117: 303-12.e1
Rudolf M, Malek G, Messinger JD, et al. (2008) Sub-retinal drusenoid deposits in human retina: organization and composition. Experimental Eye Research. 87: 402-8
Baer CA, Rickman CB, Srivastava S, et al. (2008) Recurrent choroidal neovascularization after macular translocation surgery with 360-degree peripheral retinectomy. Retina (Philadelphia, Pa.). 28: 1221-7
Malek G, Jamison JA, Mace B, et al. (2008) ERG responses and microarray analysis of gene expression in a multifactorial murine model of age-related retinal degeneration. Advances in Experimental Medicine and Biology. 613: 165-70
Malek G, Mace B, Saloupis P, et al. (2006) Initial observations of key features of age-related macular degeneration in APOE targeted replacement mice. Advances in Experimental Medicine and Biology. 572: 109-17
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