James D. Johnson
Affiliations: | University of British Columbia, Vancouver, Vancouver, BC, Canada |
Area:
DiabetesWebsite:
http://diabetes.ubc.ca/primary-members/dr-james-d-johnson/Google:
"James Johnson"Parents
Sign in to add mentor| Stanley Misler | post-doc | 2000-2004 | Washington University (Neurotree) |
| Kenneth S Polonsky | post-doc | 2000-2004 | Washington University |
Children
Sign in to add trainee| Emilyn Alejandro | grad student | UBC (Neurotree) | |
| Yu Hsuan Carol | grad student | UBC | |
| Gareth E. Lim | grad student | UBC | |
| Nicole Templeman | grad student | 2015 | UBC |
| Dan S Luciani | post-doc | UBC |
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Publications
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| Kolic J, Sun WG, Cen HH, et al. (2024) Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Medrxiv : the Preprint Server For Health Sciences |
| Kolic J, Sun WG, Johnson JD, et al. (2023) Amino acid-stimulated insulin secretion: a path forward in type 2 diabetes. Amino Acids |
| Zhang AMY, Xia YH, Lin JSH, et al. (2023) Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation. Cell Metabolism |
| Chu CMJ, Modi H, Ellis C, et al. (2022) Dynamic Ins2 Gene Activity Defines β-cell Maturity States. Diabetes |
| Skovsø S, Panzhinskiy E, Kolic J, et al. (2022) Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nature Communications. 13: 735 |
| Cen HH, Hussein B, Botezelli JD, et al. (2022) Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22088 |
| Johnson JD. (2021) On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes. Diabetologia |
| Yong J, Johnson JD, Arvan P, et al. (2021) Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus. Nature Reviews. Endocrinology |
| Zhang AMY, Wellberg EA, Kopp JL, et al. (2021) Hyperinsulinemia in Obesity, Inflammation, and Cancer. Diabetes & Metabolism Journal |
| Kolic J, Beet L, Overby P, et al. (2020) Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. Endocrinology |