C. Leigh Allen, Ph.D.

Affiliations: 
2002-2006 Chemistry Wake Forest University, Winston-Salem, NC, United States 
 2006-2011 Chemistry Duke University, Durham, NC 
 2011-2014 Structural Biology Hauptman-Woodward Medical Research Institute 
 2014-2016 Structural & Molecular Biochemistry North Carolina State University, Raleigh, NC 
 2016-2022 Medicinal Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
 2022- Contraception Research NIH (NICHD) 
Area:
x-ray crystallography, chemical biology, protein purification, biochemistry, carbohydrate synthesis, reproductive biology
Website:
http://www.cleighallen.com
Google:
"C. Leigh Allen"
Mean distance: 8.09
 
SNBCP
Cross-listing: Crystallography Tree

Parents

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S. Bruce King research assistant Wake Forest
Dewey G. McCafferty grad student 2006-2011 Duke
 (Insights into the Structure and Mechanism of Anhydromuramic Acid Kinase (AnmK): A Novel Peptidoglycan Recycling Enzyme with Dual Hydrolase and Kinase Functionality.)
Andrew M. Gulick post-doc 2011-2014 Hauptman-Woodward Medical Research Institute
John Cavanagh post-doc 2014-2016 NCSU
Daniel Johnston research scientist 2022- NIH
 (Program Officer)
Gunda I. Georg research scientist 2016-2022 UMN
 (research analyst/grant coordinator/program manager/assistant)
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Publications

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Drake EJ, Miller BR, Shi C, et al. (2016) Structures of two distinct conformations of holo-non-ribosomal peptide synthetases. Nature. 529: 235-8
Kholodar SA, Allen CL, Gulick AM, et al. (2015) The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces. Journal of the American Chemical Society. 137: 2748-56
Allen CL, Gulick AM. (2014) Structural and bioinformatic characterization of an Acinetobacter baumannii type II carrier protein. Acta Crystallographica. Section D, Biological Crystallography. 70: 1718-25
Kholodar SA, Tombline G, Liu J, et al. (2014) Alteration of the flexible loop in 1-deoxy-D-xylulose-5-phosphate reductoisomerase boosts enthalpy-driven inhibition by fosmidomycin. Biochemistry. 53: 3423-31
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