Christopher S. Chen

Affiliations:	Bioengineering	University of Pennsylvania, Philadelphia, PA, United States
	Biomedical Engineering	Boston University, Boston, MA, United States
	Wyss Insitute	Harvard University, Cambridge, MA, United States

Area:

Tissue Microfabrication

Parents

Donald E. Ingber	grad student	1997	Harvard-MIT Division of Health Sciences and Technology (Neurotree)
(Cell Shape and Integrins: Determinants of Extracellular Matrix Regulation of Growth and Survival)
George M. Whitesides	grad student	1997	Harvard-MIT Division of Health Sciences and Technology (Chemistry Tree)

Children

Christopher Lemmon	grad student
Hyun-Ho Song	grad student	2014-	Harvard-MIT Division of Health Sciences and Technology (Chemistry Tree)
Kehan Zhang	grad student	2015-	Boston University (Chemistry Tree)
Juliann Tefft	grad student	2016-	Boston University (Chemistry Tree)
Shoshana Das	grad student	2017-	Harvard-MIT Division of Health Sciences and Technology (Chemistry Tree)
Keith Gagnon	grad student	2017-	Boston University (Chemistry Tree)
Megan Griebel	grad student	2017-	Boston University (Chemistry Tree)
Christos Michas	grad student	2017-	Boston University (Chemistry Tree)
Jourdan Ewoldt	grad student	2018-	Boston University (Chemistry Tree)
Alex Lammers	grad student	2018-	Boston University (Chemistry Tree)
Amy Stoddard	grad student	2019-	Boston University (Chemistry Tree)
Anish Vasan	grad student	2020-	Boston University (Chemistry Tree)
Celeste M. Nelson	grad student	2004	Johns Hopkins (Chemistry Tree)
Monica Tanase	grad student	2004	Johns Hopkins (Chemistry Tree)
Darren S. Gray	grad student	2005	Johns Hopkins (Chemistry Tree)
Anne Hultgren	grad student	2005	Johns Hopkins (Chemistry Tree)
John L. Tan	grad student	2005	Johns Hopkins (Chemistry Tree)
Rowena McBeath	grad student	2006	Johns Hopkins (Chemistry Tree)
Sami Alom Ruiz	grad student	2008	Johns Hopkins (Chemistry Tree)
Ted T. Lee	grad student	2008-2009	Penn (Chemistry Tree)
Brian C. DiPaolo	grad student	2010	Penn (Chemistry Tree)
Zhijun Liu	grad student	2010	Penn (Chemistry Tree)
Srivatsan Raghavan	grad student	2010	Johns Hopkins (Chemistry Tree)
Colette Shen	grad student	2010	Penn (Chemistry Tree)
Ling Dong	grad student	2011	Penn (Chemistry Tree)
Jennifer L. Leight	grad student	2011	Penn (Chemistry Tree)
Michael T. Yang	grad student	2011	Penn (Chemistry Tree)
Ravi A. Desai	grad student	2004-2011	Penn (Chemistry Tree)
Jan D. Baranski	grad student	2012	Penn (Chemistry Tree)
Wesley R. Legant	grad student	2012	Penn (Chemistry Tree)
Grace Lin	grad student	2008-2012	Penn (Chemistry Tree)
Ritika Chaturvedi	grad student	2010-2013	Penn (Chemistry Tree)
Susie Cha	grad student	2012-2013	Penn (Chemistry Tree)
Angelo Sibilio	grad student	2012-2013	Penn (Chemistry Tree)
Brandon L. Blakely	grad student	2014	Penn (Chemistry Tree)
Duc-Huy Nguyen	grad student	2009-2016	Boston University, Wyss Institute (Chemistry Tree)
Sarah Stapleton	grad student	2010-2016	Boston University, Wyss Institute (Chemistry Tree)
Natalia Rodriguez	grad student	2011-2016	Boston University, Wyss Institute (Chemistry Tree)
Christopher Yu	grad student	2012-2016	Penn (Chemistry Tree)
Catherine Cheng	grad student	2014-2016	Penn (Chemistry Tree)
Daniel Cheng	grad student	2012-2018	Boston University, Wyss Institute (Chemistry Tree)
Christine Yoon	grad student	2013-2018	Boston University, Wyss Institute (Chemistry Tree)
Rebeccah Luu	grad student	2016-2018	Boston University (Chemistry Tree)
Anant Chopra	post-doc		(Physics Tree)
Esak Lee	post-doc		(Biomechanics Tree)
Ruogang Zhao	post-doc		Penn
Joe Tien	post-doc	1999-2001	Johns Hopkins Medical School (Biomechanics Tree)

Collaborators

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Publications

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Lee E, Chan SL, Lee Y, et al. (2023) A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308941120
Griebel M, Vasan A, Chen C, et al. (2023) Fibroblast clearance of damaged tissue following laser ablation in engineered microtissues. Apl Bioengineering. 7: 016112
Moore J, Ewoldt J, Venturini G, et al. (2023) Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling. International Journal of Molecular Sciences. 24
Paul I, Bolzan D, Youssef A, et al. (2023) Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT. Nature Communications. 14: 688
Das SL, Sutherland BP, Lejeune E, et al. (2022) Mechanical response of cardiac microtissues to acute localized injury. American Journal of Physiology. Heart and Circulatory Physiology. 323: H738-H748
Michas C, Karakan MÇ, Nautiyal P, et al. (2022) Engineering a living cardiac pump on a chip using high-precision fabrication. Science Advances. 8: eabm3791
Tefft JB, Bays JL, Lammers A, et al. (2021) Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature. American Journal of Physiology. Cell Physiology
Zhang K, Cloonan PE, Sundaram S, et al. (2021) Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Science Advances. 7: eabh3995
Zhao B, Zhang K, Chen CS, et al. (2021) Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes. Plos Computational Biology. 17: e1009443
Javor J, Ewoldt JK, Cloonan PE, et al. (2021) Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue. Microsystems & Nanoengineering. 7: 10

Christopher S. Chen

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