Simon T. Nevin

Affiliations: 
2004-2009 School of Biomedical Sciences University of Queensland, Saint Lucia, Queensland, Australia 
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Muttenthaler M, Nevin ST, Inserra M, et al. (2020) On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. Australian Journal of Chemistry. 73: 327-333
Hopping G, Wang CI, Hogg RC, et al. (2014) Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42
Knapp O, Nevin ST, Yasuda T, et al. (2012) Biophysical properties of Na(v) 1.8/Na(v) 1.2 chimeras and inhibition by µO-conotoxin MrVIB. British Journal of Pharmacology. 166: 2148-60
de Araujo AD, Callaghan B, Nevin ST, et al. (2011) Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9
Daly NL, Callaghan B, Clark RJ, et al. (2011) Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237
Klimis H, Adams DJ, Callaghan B, et al. (2011) A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152: 259-66
Lovelace ES, Gunasekera S, Alvarmo C, et al. (2011) Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization Antioxidants and Redox Signaling. 14: 87-95
Clark RJ, Jensen J, Nevin ST, et al. (2010) The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548
Muttenthaler M, Nevin ST, Grishin AA, et al. (2010) Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22
Clark R, Jensen J, Nevin S, et al. (2010) Inside Cover: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. Int. Ed. 37/2010) Angewandte Chemie International Edition. 49: 6460-6460
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