Karen Mruk

Affiliations: 
2005-2012 Biochemistry and Molecular Pharmacology University of Massachusetts Medical School, Worcester, MA, United States 
 2012-2018 Chemical and Systems Biology Stanford University, Palo Alto, CA 
 2018- School of Pharmacy University of Wyoming, Laramie, WY, United States 
Area:
zebrafish models of CNS injury, optogenetics
Google:
"Karen Mruk"
Bio:

https://profiles.stanford.edu/karen-mruk
Mruk, K. Small Molecule Investigation of KCNQ Potassium Channels: A Dissertation. (2012). University of Massachusetts Medical School. GSBS Dissertations and Theses. Paper 621. https://escholarship.umassmed.edu/gsbs_diss/621

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Parents

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William Rudolf Kobertz grad student 2005-2012 University of Massachusetts Medical School
 (Small Molecule Investigation of KCNQ Potassium Channels.)
James K. Chen post-doc 2012-2018 Stanford
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Publications

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Hwang S, Mruk K, Rahighi S, et al. (2018) Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nature Communications. 9: 4045
Öktem EK, Mruk K, Chang J, et al. (2016) Erratum to: Mutant SOD1 protein increases Nav1.3 channel excitability. Journal of Biological Physics
Kubat Öktem E, Mruk K, Chang J, et al. (2016) Mutant SOD1 protein increases Nav1.3 channel excitability. Journal of Biological Physics
Mruk K, Kobertz WR. (2015) Bioreactive Tethers. Advances in Experimental Medicine and Biology. 869: 77-100
Mruk K, Chen JK. (2015) Thinking big with small molecules. The Journal of Cell Biology. 209: 7-9
Mruk K, Farley BM, Ritacco AW, et al. (2014) Calmodulation meta-analysis: predicting calmodulin binding via canonical motif clustering. The Journal of General Physiology. 144: 105-14
Mruk K, Shandilya SM, Blaustein RO, et al. (2012) Structural insights into neuronal K+ channel-calmodulin complexes. Proceedings of the National Academy of Sciences of the United States of America. 109: 13579-83
O'Connell D, Mruk K, Rocheleau JM, et al. (2011) Xenopus laevis oocytes infected with multi-drug-resistant bacteria: implications for electrical recordings. The Journal of General Physiology. 138: 271-7
Mruk K, Kobertz WR. (2009) Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes. Plos One. 4: e4236
Clancy L, Mruk K, Archer K, et al. (2005) Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18099-104
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