Simon Vu

2015-2020 University of California, Davis, Davis, CA 
 2020- Van Andel Institute 
TRP Channels
"Simon Vu"
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Jie Zheng grad student 2015-2020 UC Davis
Juan Du post-doc 2020- Van Andel Institute (Chemistry Tree)
Wei Lü post-doc 2020- Van Andel Institute (Chemistry Tree)
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Vu S, Singh V, Wulff H, et al. (2020) New capsaicin analogs as molecular rulers to define the permissive conformation of the mouse TRPV1 ligand-binding pocket. Elife. 9
Liu C, Reese R, Vu S, et al. (2020) A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. Neuron
Du G, Tian Y, Yao Z, et al. (2020) A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds. The Journal of Biological Chemistry
Zhu A, Aierken A, Yao Z, et al. (2020) A centipede toxin causes rapid desensitization of nociceptor TRPV1 ion channel. Toxicon : Official Journal of the International Society On Toxinology
Vu S, Singh V, Yang F, et al. (2020) A Set of Novel Capsaicin Analogs as Molecular Ruler for Conformational Change of the TRPV1 Ligand-Binding Pocket Biophysical Journal. 118: 411a
Dong Y, Yin Y, Vu S, et al. (2019) A distinct structural mechanism underlies TRPV1 activation by piperine. Biochemical and Biophysical Research Communications
Yin Y, Dong Y, Vu S, et al. (2019) Structural Mechanism Underlying TRPV1 Activation by Pungent Compounds in Gingers. British Journal of Pharmacology
Vu S, Hyun Lee B, Xiao X, et al. (2019) Short- and Long-Distance Allosteric Coupling in Capsaicin-Induced TRPV1 Activation Biophysical Journal. 116: 533a-534a
Wang H, Xu Z, Hyun Lee B, et al. (2019) Gain-Of-Function Mutationsin TRPM4 Activation Gate Cause Skin Disease PSEK Biophysical Journal. 116: 452a
Wang H, Xu Z, Lee BH, et al. (2018) Gain-of-function mutations in TRPM4 activation gate cause progressive symmetric erythrokeratoderma. The Journal of Investigative Dermatology
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