David E. Jane, PhD

Affiliations: 
Pharmacology University of Bristol, Bristol, England, United Kingdom 
Area:
Glutamate pharmacology and medicinal chemistry
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"David Jane"
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Publications

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Collingridge GL, Evans RH, Jane DE, et al. (2023) Jeffrey Clifton Watkins FRS - The father of the glutamate receptor. Neuropharmacology. 109650
Rečnik LM, Thatcher RJ, Mallah S, et al. (2021) Synthesis and pharmacological characterisation of arctigenin analogues as antagonists of AMPA and kainate receptors. Organic & Biomolecular Chemistry. 19: 9154-9162
Eapen AV, Fernández-Fernández D, Georgiou J, et al. (2021) Multiple roles of GluN2D-containing NMDA receptors in short-term potentiation and long-term potentiation in mouse hippocampal slices. Neuropharmacology. 201: 108833
Sapkota K, Burnell ES, Irvine MW, et al. (2021) Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792. Neuropharmacology. 201: 108818
Wang JX, Irvine MW, Burnell ES, et al. (2020) Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nature Communications. 11: 423
Sapkota K, Dore K, Tang K, et al. (2019) The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators. Biochemical Pharmacology. 159: 140-153
Irvine MW, Fang G, Sapkota K, et al. (2018) Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid. European Journal of Medicinal Chemistry. 164: 471-498
Scholefield CL, Atlason PT, Jane DE, et al. (2018) Assembly and Trafficking of Homomeric and Heteromeric Kainate Receptors with Impaired Ligand Binding Sites. Neurochemical Research
Lodge D, Watkins JC, Bortolotto ZA, et al. (2018) The 1980s: D-AP5, LTP and a Decade of NMDA Receptor Discoveries. Neurochemical Research
Ingram R, Kang H, Lightman S, et al. (2018) Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity. Neuropharmacology
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