Andrew E. Arrant, PhD

Affiliations: 
Neurology University of Alabama, Birmingham, Birmingham, AL, United States 
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"Andrew Arrant"
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Cynthia Moreton Kuhn grad student 2007-2012 Duke
 (Why Does Risk-Taking Peak During Adolescence?: Contribution of Neurochemical and Circuit-Level Function to Lower Serotonin-Mediated Behavioral Inhibition in Adolescents.)
Erik Roberson post-doc 2013-2019 UAB
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Publications

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Kaplelach AK, Fox SN, Cook AK, et al. (2023) Regulation of extracellular progranulin in medial prefrontal cortex. Neurobiology of Disease. 188: 106326
Kurnellas M, Mitra A, Schwabe T, et al. (2023) Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia. Journal of Translational Medicine. 21: 387
Davis SE, Cook AK, Hall JA, et al. (2023) Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta Neuropathologica Communications. 11: 70
Davis SE, Roth JR, Aljabi Q, et al. (2021) Delivering progranulin to neuronal lysosomes protects against excitotoxicity. The Journal of Biological Chemistry. 100993
Arrant AE, Davis SE, Vollmer RM, et al. (2020) Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Annals of Clinical and Translational Neurology
Arrant AE, Roth JR, Boyle NR, et al. (2019) Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathologica Communications. 7: 218
Stoyka LE, Arrant AE, Thrasher DR, et al. (2019) Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions. Neurobiology of Disease. 104708
Arrant AE, Boyle NR, Roth JR, et al. (2019) P1-186: IMPAIRED β-GLUCOCEREBROSIDASE ACTIVITY AND PROCESSING IN FRONTOTEMPORAL DEMENTIA DUE TO PROGRANULIN MUTATIONS Alzheimers & Dementia. 15
Arrant AE, Filiano AJ, Patel AR, et al. (2018) Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice. Neurobiology of Disease
Arrant AE, Nicholson AM, Zhou X, et al. (2018) Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency. Molecular Neurodegeneration. 13: 32
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