Marc P Forrest

Affiliations: 
Northwestern University, Evanston, IL 
Area:
neurodevelopmental and psychiatric disorders
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"Marc Forrest"
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Publications

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Zhang S, Zhang H, Forrest MP, et al. (2023) Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons. Cell Genomics. 3: 100399
Forrest MP, Penzes P. (2023) Mechanisms of copy number variants in neuropsychiatric disorders: From genes to therapeutics. Current Opinion in Neurobiology. 82: 102750
Yoon S, Santos MD, Forrest MP, et al. (2023) Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome. Cell Reports. 42: 112784
Forrest MP, Dos Santos M, Piguel NH, et al. (2023) Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature Communications. 14: 825
Parnell E, Culotta L, Forrest MP, et al. (2022) Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons. Biological Psychiatry
Kozlova A, Zhang S, Kotlar AV, et al. (2022) Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons. American Journal of Human Genetics. 109: 1500-1519
Martín-de-Saavedra MD, Dos Santos M, Culotta L, et al. (2021) Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca homeostasis and network synchrony via PMCA2/ATP2B2. Neuron
Simkin D, Marshall KA, Vanoye CG, et al. (2021) Dyshomeostatic modulation of Ca-activated K channels in a human neuronal model of KCNQ2 encephalopathy. Elife. 10
Forrest MP, Penzes P. (2020) Autism Genetics: Over 100 Risk Genes and Counting. Pediatric Neurology Briefs. 34: 13
Parnell E, Shapiro LP, Voorn RA, et al. (2020) KALRN: A central regulator of synaptic function and synaptopathies. Gene. 145306
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