Richard Lonsdale
Affiliations: | University of Oxford, Oxford, United Kingdom |
Area:
Computational neuroscienceGoogle:
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Publications
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| Lonsdale R, Ward RA. (2018) Structure-based design of targeted covalent inhibitors. Chemical Society Reviews |
| Qu G, Lonsdale R, Yao P, et al. (2018) Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis. Chembiochem : a European Journal of Chemical Biology |
| Acevedo-Rocha CG, Gamble CG, Lonsdale R, et al. (2018) P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping Acs Catalysis. 8: 3395-3410 |
| Li G, Yao P, Gong R, et al. (2017) Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N. Chemical Science. 8: 4093-4099 |
| Sun Z, Wu L, Bocola M, et al. (2017) Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations. Journal of the American Chemical Society |
| Lonsdale R, Burgess J, Colclough N, et al. (2017) Expanding the Armory: Predicting and Tuning Covalent Warhead Reactivity. Journal of Chemical Information and Modeling |
| Li A, Ilie A, Sun Z, et al. (2016) Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie (International Ed. in English) |
| Sun Z, Lonsdale R, Li G, et al. (2016) Comparing Different Strategies in Directed Evolution of Enzyme Stereoselectivity: Single versus Double Code Saturation Mutagenesis. Chembiochem : a European Journal of Chemical Biology |
| Wang JB, Lonsdale R, Reetz MT. (2016) Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation. Chemical Communications (Cambridge, England) |
| Lonsdale R, Fort RM, Rydberg P, et al. (2016) Quantum mechanics/molecular mechanics modeling of drug metabolism: Mexiletine N-hydroxylation by cytochrome P450 1A2. Chemical Research in Toxicology |