Jaclyn N. Highland
Affiliations: | 2015- | University of Maryland at Baltimore, Baltimore, MD, United States |
Area:
Neuropharmacology, Neuropsychopharmacology, Behavioral NeuroscienceGoogle:
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Publications
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| Georgiou P, Zanos P, Mou TM, et al. (2022) Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nature Neuroscience |
| Highland JN, Morris PJ, Konrath KM, et al. (2022) Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523 |
| Highland JN, Farmer CA, Zanos P, et al. (2021) Sex-dependent metabolism of ketamine and ()-hydroxynorketamine in mice and humans. Journal of Psychopharmacology (Oxford, England). 2698811211064922 |
| Highland JN, Zanos P, Riggs LM, et al. (2021) Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791 |
| Wang AQ, Konrath KM, Highland JN, et al. (2020) P199 - HILIC UPLC-MS/MS methods for the assessment of hydroxynorketamines pharmacokinetics in mouse plasma and brain Drug Metabolism and Pharmacokinetics. 35 |
| Zanos P, Highland JN, Liu X, et al. (2019) (R)-ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anesthetic doses. British Journal of Pharmacology |
| Highland JN, Zanos P, Georgiou P, et al. (2019) Group II metabotropic glutamate receptor blockade promotes stress resilience in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology |
| Zanos P, Highland JN, Stewart BW, et al. (2019) ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America |
| Highland JN, Morris PJ, Zanos P, et al. (2018) Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine. Journal of Psychopharmacology (Oxford, England). 269881118812095 |
| Zanos P, Moaddel R, Morris PJ, et al. (2018) Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660 |