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William C. Hahn, M.D., Ph.D.

Affiliations: 
Molecular and Cellular Oncology, Medical Oncology Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT, 
Area:
EGFR , RNAi
Website:
http://research4.dfci.harvard.edu/hahnlab//index.html
Google:
"William Hahn"
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Parents

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Robert A. Weinberg grad student (Chemistry Tree)

Children

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Andrew Lee Hong grad student
Andrew Aguirre post-doc Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT,
Priscilla Brastianos post-doc Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT,
Ian Dunn post-doc
Elsa Beyer Beyer Krall post-doc Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT,

Collaborators

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National Brain Tumor Society collaborator Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT,
BETA: Related publications

Publications

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Schaefer A, Hodge RG, Zhang H, et al. (2023) RHOA drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science Signaling. 16: eadg5289
Krill-Burger JM, Dempster JM, Borah AA, et al. (2023) Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal. Genome Biology. 24: 192
de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, et al. (2023) Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature Cancer. 4: 754-773
Perurena N, Lock R, Davis RA, et al. (2023) USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. Cell Reports. Medicine. 101007
Sharifnia T, Wawer MJ, Goodale A, et al. (2023) Mapping the landscape of genetic dependencies in chordoma. Nature Communications. 14: 1933
Bala P, Rennhack JP, Aitymbayev D, et al. (2023) Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Science Advances. 9: eadf0927
Cervia LD, Shibue T, Borah AA, et al. (2022) A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer Discovery
Schröfelbauer B, Kimes PK, Hauke P, et al. (2022) Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America. 120: e2206751120
Hagel KR, Arafeh R, Gang S, et al. (2022) Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer Research
Williams HL, Dias Costa A, Zhang J, et al. (2022) Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity. Cancer Research
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