Wei Hong
Affiliations: | Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States |
Area:
Alzheimer's diseaseGoogle:
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Publications
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| Wang Z, Jin M, Hong W, et al. (2023) Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics. Acta Neuropathologica Communications. 11: 39 |
| Hong W, Liu W, Desousa AO, et al. (2023) Methods for the isolation and analysis of Aβ from postmortem brain. Frontiers in Neuroscience. 17: 1108715 |
| Corbett GT, Wang Z, Hong W, et al. (2019) PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins. Acta Neuropathologica |
| Zott B, Simon MM, Hong W, et al. (2019) A vicious cycle of β amyloid-dependent neuronal hyperactivation. Science (New York, N.Y.). 365: 559-565 |
| Brinkmalm G, Hong W, Wang Z, et al. (2019) Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain. Brain : a Journal of Neurology. 142: 1441-1457 |
| Mengel D, Hong W, Corbett GT, et al. (2018) PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity. Brain Research |
| Ondrejcak T, Klyubin I, Corbett GT, et al. (2018) Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
| Jin M, O'Nuallain B, Hong W, et al. (2018) An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer's disease. Nature Communications. 9: 2676 |
| Hong W, Wang Z, Liu W, et al. (2018) Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer's disease brain. Acta Neuropathologica |
| Wang Z, Jackson RJ, Hong W, et al. (2017) Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |