John O Diraddo
Affiliations: | 2009-2014 | Pharmacology | Georgetown University, Washington, DC |
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| Bhattacharya S, Khatri A, Swanger SA, et al. (2018) Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 99: 315-328.e5 |
| Swanger SA, Vance KM, Acker TM, et al. (2017) A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons. Acs Chemical Neuroscience |
| Perszyk RE, DiRaddo JO, Strong KL, et al. (2016) GluN2D-containing NMDA receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity. Molecular Pharmacology |
| Cox BD, Mehta AK, DiRaddo JO, et al. (2015) Structural analysis of CXCR4 - Antagonist interactions using saturation-transfer double-difference NMR. Biochemical and Biophysical Research Communications. 466: 28-32 |
| DiRaddo JO, Miller EJ, Bowman-Dalley C, et al. (2015) Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors. Molecular Pharmacology. 88: 450-9 |
| Gelb T, Pshenichkin S, Rodriguez OC, et al. (2015) Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas. Oncogene. 34: 2711-20 |
| DiRaddo JO, Miller EJ, Hathaway HA, et al. (2014) A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 373-82 |
| DiRaddo JO, Pshenichkin S, Gelb T, et al. (2013) Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor. Gene. 519: 367-73 |
| Emery AC, DiRaddo JO, Miller E, et al. (2012) Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling. Molecular Pharmacology. 82: 291-301 |