Nael Nadif Kasri, Ph.D

Cns Radboud university medical centre 
Synaptic plasticity, epigenetics, intellectual disability
"Nael Nadif Kasri"
Mean distance: 16.86 (cluster 6)
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Wang S, Rhijn JV, Akkouh I, et al. (2022) Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway. Cell Reports. 39: 110790
van Rhijn JR, Shi Y, Bormann M, et al. (2021) Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons. Neurobiology of Disease. 163: 105587
Wang S, Bleeck A, Nadif Kasri N, et al. (2021) SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders. Frontiers in Molecular Neuroscience. 14: 772000
Linda K, Lewerissa EI, Verboven AHA, et al. (2021) Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders. Autophagy. 1-20
Mossink B, van Rhijn JR, Wang S, et al. (2021) Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. Molecular Psychiatry
Schörnig M, Ju X, Fast L, et al. (2021) Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes. Elife. 10
Mossink B, Negwer M, Schubert D, et al. (2020) The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective. Cellular and Molecular Life Sciences : Cmls
Negwer M, Piera K, Hesen R, et al. (2020) EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Structure & Function
Klein Gunnewiek TM, Van Hugte EJH, Frega M, et al. (2020) m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity. Cell Reports. 31: 107538
Frega M, Selten M, Mossink B, et al. (2020) Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype. Cell Reports. 30: 173-186.e6
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