Gabriele Lignani

Affiliations: 
UCL Institute of Neurology, London, England, United Kingdom 
Area:
Neuroscience
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"Gabriele Lignani"
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Parents

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Fabio Benfenati grad student 2009-2014
Schorge Stephanie post-doc 2014-2016
Dimitri Kullmann post-doc 2016-2018

Children

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Eleonora Lugara' grad student 2016-
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Publications

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Almacellas Barbanoj A, Graham RT, Maffei B, et al. (2023) Anti-seizure gene therapy for focal cortical dysplasia. Brain : a Journal of Neurology
Moschetta M, Ravasenga T, De Fusco A, et al. (2022) Ca binding to synapsin I regulates resting Ca and recovery from synaptic depression in nerve terminals. Cellular and Molecular Life Sciences : Cmls. 79: 600
Qiu Y, O'Neill N, Maffei B, et al. (2022) On-demand cell-autonomous gene therapy for brain circuit disorders. Science (New York, N.Y.). 378: 523-532
Prestigio C, Ferrante D, Marte A, et al. (2021) REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion. Elife. 10
Turner TJ, Zourray C, Schorge S, et al. (2020) Recent advances in gene therapy for neurodevelopmental disorders with epilepsy. Journal of Neurochemistry
Lignani G, Baldelli P, Marra V. (2020) Homeostatic Plasticity in Epilepsy. Frontiers in Cellular Neuroscience. 14: 197
Colasante G, Qiu Y, Massimino L, et al. (2020) In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Brain : a Journal of Neurology
Colasante G, Lignani G, Brusco S, et al. (2019) dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy
Lugarà E, De Fusco A, Lignani G, et al. (2019) Synapsin I Controls Synaptic Maturation of Long-Range Projections in the Lateral Amygdala in a Targeted Selective Fashion. Frontiers in Cellular Neuroscience. 13: 220
Weston M, Kaserer T, Wu A, et al. (2019) Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics. Science Advances. 5: eaaw1567
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