Abraham J. Al-Ahmad, Ph.D.

Affiliations: 
2004-2009 Veterinary Physiology Universität Zürich, Zürich, ZH, Switzerland 
 2009-2011 Molecular & Cellular Medicine Texas A&M Health Science Center, Bryan, TX, United States 
 2011-2014 Chemical & Biological Engineering University of Wisconsin, Madison, Madison, WI 
 2014- Pharmaceutical Sciences Texas Tech University Health Sciences Center 
Area:
Blood-brain barrier, Hypoxia, Stroke, Alzheimer's disease, GLUT1 deficiency syndrome
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Publications

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Al-Ahmad AJ. (2023) Human-Induced Pluripotent Stem Cell-Based Model of the Blood-Brain at 10 Years: A Retrospective on Past and Current Disease Models. Handbook of Experimental Pharmacology
Noorani B, Chowdhury EA, Alqahtani F, et al. (2023) Effects of Volatile Anesthetics Versus Ketamine on Blood-Brain Barrier Permeability via Lipid-Mediated Alterations of Endothelial Cell Membranes. The Journal of Pharmacology and Experimental Therapeutics
Pervaiz I, Zahra FT, Mikelis C, et al. (2022) An in vitro model of glucose transporter 1 deficiency syndrome at the blood-brain barrier using induced pluripotent stem cells. Journal of Neurochemistry
Pervaiz I, Al-Ahmad AJ. (2022) In Vitro Models of the Human Blood-Brain Barrier Utilising Human Induced Pluripotent Stem Cells: Opportunities and Challenges. Methods in Molecular Biology (Clifton, N.J.). 2492: 53-72
Raut S, Patel R, Pervaiz I, et al. (2022) Abeta peptides disrupt the barrier integrity and glucose metabolism of human induced pluripotent stem cell-derived brain microvascular endothelial cells. Neurotoxicology. 89: 110-120
Al-Ahmad AJ, Pervaiz I, Karamyan VT. (2021) Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model. Journal of Neuroendocrinology. 33: e12931
Raut S, Patel R, Al-Ahmad AJ. (2021) Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro. Fluids and Barriers of the Cns. 18: 3
Kinarivala N, Morsy A, Patel R, et al. (2020) An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening. Acs Pharmacology & Translational Science. 3: 931-947
Nozohouri S, Noorani B, Al-Ahmad A, et al. (2020) Estimating Brain Permeability Using In Vitro Blood-Brain Barrier Models. Methods in Molecular Biology (Clifton, N.J.)
Albekairi TH, Vaidya B, Patel R, et al. (2019) Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP). Pharmaceutics. 11
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