Melih Acar

Affiliations: 
Scientist Celgene 
 2008-2015 Children's Research Institute University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States 
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"Melih Acar"
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Publications

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Lee S, Song JJ, Beyer LA, et al. (2020) Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea. Scientific Reports. 10: 21397
Durdagi S, Aksoydan B, Erol I, et al. (2017) Integration of multi-scale molecular modeling approaches with experiments for the in silico guided design and discovery of novel hERG-Neutral antihypertensive oxazalone and imidazolone derivatives and analysis of their potential restrictive effects on cell proliferation. European Journal of Medicinal Chemistry. 145: 273-290
Shimada IS, Acar M, Burgess RJ, et al. (2017) Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells. Genes & Development
Inra CN, Zhou BO, Acar M, et al. (2015) A perisinusoidal niche for extramedullary haematopoiesis in the spleen. Nature
Acar M, Kocherlakota KS, Murphy MM, et al. (2015) Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal. Nature. 526: 126-30
Rajagopalan KN, Egnatchik RA, Calvaruso MA, et al. (2015) Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells. Cancer & Metabolism. 3: 7
Kiel MJ, Acar M, Radice GL, et al. (2009) Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance. Cell Stem Cell. 4: 170-9
Tien AC, Rajan A, Schulze KL, et al. (2008) Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. The Journal of Cell Biology. 182: 1113-25
Acar M, Jafar-Nejad H, Takeuchi H, et al. (2008) Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. Cell. 132: 247-58
Childress JL, Acar M, Tao C, et al. (2006) Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Current Biology : Cb. 16: 2228-33
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