Joel C. Watts
Affiliations: | 2003-2008 | Centre for Research in Neurodegenerative Diseases | University of Toronto, Toronto, ON, Canada |
| 2008-2014 | Institute for Neurodegenerative Diseases, Department of Neurology | University of California, San Francisco, San Francisco, CA | |
| 2014- | Tanz Centre for Research in Neurodegenerative Diseases, Department of Biochemistry | University of Toronto, Toronto, ON, Canada |
Website:
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Children
Sign in to add trainee| Matthew Bourkas | grad student | 2014- | University of Toronto |
| Heather H. C. Lau | grad student | 2014- | University of Toronto |
| Hamza Arshad | grad student | 2015- | University of Toronto |
| Raphaella W. L. So | grad student | 2017- | University of Toronto |
| Alison Mao | grad student | 2020- | University of Toronto |
| Angus Lau | grad student | 2015-2018 | University of Toronto |
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Publications
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| Walsh DJ, Rees JR, Mehra S, et al. (2023) Anti-prion drugs do not improve survival in knock-in models of inherited prion disease. Biorxiv : the Preprint Server For Biology |
| Lau HHC, Martinez-Valbuena I, So RWL, et al. (2023) The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson's disease. Acta Neuropathologica Communications. 11: 72 |
| So RWL, Watts JC. (2023) α-Synuclein Conformational Strains as Drivers of Phenotypic Heterogeneity in Neurodegenerative Diseases. Journal of Molecular Biology. 168011 |
| Williams D, Yan BQ, Wang H, et al. (2023) Somatostatin slows Aβ plaque deposition in aged APP mice by blocking Aβ aggregation. Scientific Reports. 13: 2337 |
| Arshad H, Patel Z, Amano G, et al. (2022) A Single Protective Polymorphism in the Prion Protein Blocks Cross-Species Prion Replication in Cultured Cells. Journal of Neurochemistry |
| Arshad H, Watts JC. (2022) Genetically engineered cellular models of prion propagation. Cell and Tissue Research |
| Williams D, Mehrabian M, Arshad H, et al. (2021) The cellular prion protein interacts with and promotes the activity of Na,K-ATPases. Plos One. 16: e0258682 |
| Arshad H, Patel Z, Mehrabian M, et al. (2021) The aminoglycoside G418 hinders de novo prion infection in cultured cells. The Journal of Biological Chemistry. 101073 |
| Ruiz-Riquelme A, Mao A, Barghash MM, et al. (2021) Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathologica Communications. 9: 83 |
| Bélondrade M, Nicot S, Mayran C, et al. (2021) Sensitive protein misfolding cyclic amplification of sporadic Creutzfeldt-Jakob disease prions is strongly seed and substrate dependent. Scientific Reports. 11: 4058 |