Alexandra L Schober, PhD

Affiliations: 
2018- Centre for Research in Neuroscience McGill University Health Centre 
Area:
Astrocytes, Alzheimer's disease
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"Alexandra Schober"
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Publications

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Martinez-Lozada Z, Farmer WT, Schober AL, et al. (2023) Cooperative and competitive regulation of the astrocytic transcriptome by neurons and endothelial cells: Impact on astrocyte maturation. Journal of Neurochemistry
Balkaya M, Dohare P, Chen S, et al. (2023) Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release. Iscience. 26: 106669
Schober AL, Wicki-Stordeur LE, Murai KK, et al. (2022) Foundations and implications of astrocyte heterogeneity during brain development and disease. Trends in Neurosciences
Rubino S, Bach MD, Schober AL, et al. (2018) Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine. Frontiers in Oncology. 8: 142
Schober AL, Wilson CS, Mongin AA. (2017) Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes. The Journal of Physiology
Schober AL, Gagarkin DA, Chen Y, et al. (2016) Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo. Frontiers in Cellular Neuroscience. 10: 262
Dohare P, Zia MT, Ahmed E, et al. (2016) AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3363-77
Schober AL, Mongin AA. (2015) Intracellular levels of glutamate in swollen astrocytes are preserved via neurotransmitter reuptake and de novo synthesis: implications for hyponatremia. Journal of Neurochemistry. 135: 176-85
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