Guy A Caldwell, Ph.D.

Affiliations: 
1999- Biological Sciences The University of Alabama, Tuscaloosa, AL 
Area:
C. elegans, genetics, molecular biology, neurodegeneration, dopamine, Parkinson's disease, Alzheimer's disease, dystonia, epilepsy
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Publications

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Gaeta AL, Willicott K, Willicott CW, et al. (2023) Mechanistic impacts of bacterial diet on dopaminergic neurodegeneration in a α-synuclein model of Parkinson's disease. Iscience. 26: 106859
Starr LA, McKay LE, Peter KN, et al. (2023) Attenuation of Dopaminergic Neurodegeneration in a Parkinson's Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2. Journal of Developmental Biology. 11
Nourse JB, Russell SN, Moniz NA, et al. (2023) Integrated regulation of dopaminergic and epigenetic effectors of neuroprotection in Parkinson's disease models. Proceedings of the National Academy of Sciences of the United States of America. 120: e2210712120
Gaeta AL, Nourse JB, Willicott K, et al. (2022) Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans. Plos Genetics. 18: e1010115
Fanning S, Cirka H, Thies JL, et al. (2022) Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy. Npj Parkinson's Disease. 8: 74
van der Welle REN, Jobling R, Burns C, et al. (2021) Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation. Embo Molecular Medicine. e13258
McGrath K, Agarwal S, Tonelli M, et al. (2021) A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6. Proceedings of the National Academy of Sciences of the United States of America. 118
Caldwell KA, Willicott CW, Caldwell GA. (2020) Modeling neurodegeneration in . Disease Models & Mechanisms. 13
Hartman JH, Gonzalez-Hunt C, Hall SM, et al. (2019) Genetic Defects in Mitochondrial Dynamics in Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration. International Journal of Molecular Sciences. 20
Gaeta AL, Caldwell KA, Caldwell GA. (2019) Found in Translation: The Utility of Alpha-Synuclein Models of Parkinson's Disease. Brain Sciences. 9
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