Valentin K. Gribkoff
Affiliations: | Knopp Neurosciences Inc., Pittsburgh, PA, United States |
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"Valentin Gribkoff"Mean distance: 14.19 (cluster 19) | S | N | B | C | P |
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| Sacchetti S, Dworetzky SI, Alavian KN, et al. (2011) Decrease in a Leak Conductance Associated with Mitochondrial Complex V and Improved Bioenergetic Efficiency may Underlie Cytoprotection of at-Risk Neurons by Dexpramipexole Biophysical Journal. 100: 459a |
| Romine JL, Martin SW, Meanwell NA, et al. (2007) 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR. Journal of Medicinal Chemistry. 50: 528-42 |
| Lindner MD, Hogan JB, Hodges DB, et al. (2006) Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping. Psychopharmacology. 188: 629-40 |
| Yang B, Gribkoff VK, Pan J, et al. (2006) Pharmacological activation and inhibition of Slack (Slo2.2) channels. Neuropharmacology. 51: 896-906 |
| Lindner MD, Hogan JB, Krause RG, et al. (2006) Soluble Abeta and cognitive function in aged F-344 rats and Tg2576 mice. Behavioural Brain Research. 173: 62-75 |
| Vrudhula VM, Dasgupta B, Boissard CG, et al. (2005) Analogs of a potent maxi-K potassium channel opener with an improved inhibitory profile toward cytochrome P450 isozymes. Bioorganic & Medicinal Chemistry Letters. 15: 4286-90 |
| Gribkoff VK, Winquist RJ. (2005) Voltage-gated cation channel modulators for the treatment of stroke. Expert Opinion On Investigational Drugs. 14: 579-92 |
| Boy KM, Guernon JM, Sit SY, et al. (2004) 3-Thio-quinolinone maxi-K openers for the treatment of erectile dysfunction. Bioorganic & Medicinal Chemistry Letters. 14: 5089-93 |
| Wu YJ, He H, Sun LQ, et al. (2004) Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers. Journal of Medicinal Chemistry. 47: 2887-96 |
| Wu YJ, Boissard CG, Chen J, et al. (2004) (S)-N-[1-(4-cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons. Bioorganic & Medicinal Chemistry Letters. 14: 1991-5 |