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Douglas E Smith

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Biophysics, Polymer Physics
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"Douglas Smith"
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Parents

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Albert J. Libchaber research assistant 1990-1992
Steven Chu grad student 1993-1999
Carlos José Bustamante post-doc 1999-2001 (Chemistry Tree)

Children

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Rachel Millin research assistant UCSD
Dorian Raymer research assistant UCSD
John Peter Rickgauer research assistant UCSD (Neurotree)
Zachary Berndsen grad student UCSD
Cody Chapman grad student UCSD
Damian delToro grad student UCSD
Derek Fuller grad student UCSD
Greg Gemmen grad student (Chemistry Tree)
Nicholas Keller grad student UCSD
Amy D. Migliori grad student UCSD (Chemistry Tree)
Mariam Ordyan grad student UCSD
Rae Robertson-Anderson grad student UCSD
James M. Tsay grad student (Chemistry Tree)
Gregory J. Gemmen grad student 2006 UCSD
Rae M. Robertson grad student 2007 UCSD
Puchun Ke post-doc UCSD
Stephan Laib post-doc UCSD

Collaborators

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Publications

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Fizari M, Keller N, Jardine PJ, et al. (2023) Role of DNA-DNA sliding friction and nonequilibrium dynamics in viral genome ejection and packaging. Nucleic Acids Research
Fizari M, Keller N, Jardine PJ, et al. (2023) Role of DNA-DNA sliding friction and non-equilibrium dynamics in viral genome ejection and packaging. Biorxiv : the Preprint Server For Biology
Mo Y, Fizari M, Koharchik K, et al. (2021) Determining Trap Compliances, Microsphere Size Variations, and Response Linearities in Single DNA Molecule Elasticity Measurements with Optical Tweezers. Frontiers in Molecular Biosciences. 8: 605102
Mo Y, Keller N, delToro D, et al. (2020) Function of a viral genome packaging motor from bacteriophage T4 is insensitive to DNA sequence. Nucleic Acids Research
Ordyan M, Fizari M, Chien J, et al. (2020) Regulation of Viral Packaging Motors Grip on DNA and Discovery of a DNA “End-Clamp” Mechanism Biophysical Journal. 118: 75a
Fizari M, Smith DE. (2020) Restricted Mobility of DNA Packaged in Phage PHI29 Viral Proheads Assessed by Single-Molecule Optical Tweezers Measurements of DNA Exit Biophysical Journal. 118: 63a
Mo Y, Keller NA, Smith DE. (2020) High GC Content DNA does not Affect Phage T4 DNA Packaging -- Test of a Scrunchworm Model for Packaging Motor Function Biophysical Journal. 118: 188a
delToro D, Ortiz D, Ordyan M, et al. (2019) Functional Dissection of a Viral DNA Packaging Machine's Walker B Motif. Journal of Molecular Biology
Smith DE, Chu S. (2019) Response of flexible polymers to a sudden elongational flow Science (New York, N.Y.). 281: 1335-40
Ordyan M, Alam I, Mahalingam M, et al. (2018) Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. Nature Communications. 9: 5434
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