Mark Moehle

2012-2015 Neurology University of Alabama, Birmingham, Birmingham, AL, United States 
"Mark Moehle"
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Moehle MS, Conn PJ. (2019) Roles of the M acetylcholine receptor in the basal ganglia and the treatment of movement disorders. Movement Disorders : Official Journal of the Movement Disorder Society
Yohn SE, Foster DJ, Covey DP, et al. (2018) Activation of the mGlu metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M muscarinic receptor allosteric modulators. Molecular Psychiatry
Moehle MS, Pancani T, Byun N, et al. (2017) Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M4 Muscarinic Receptor. Neuron. 96: 1358-1372.e4
Walker AG, Sheffler DJ, Lewis AS, et al. (2017) Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP, Long-Term Potentiation, and Disrupts Memory Reconsolidation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Abdelmotilib H, Maltbie T, Delic V, et al. (2017) α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration. Neurobiology of Disease
Fraser KB, Moehle MS, Alcalay RN, et al. (2016) Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers. Neurology. 86: 994-9
Pancani T, Foster DJ, Moehle MS, et al. (2015) Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 14078-83
Daher JP, Abdelmotilib HA, Hu X, et al. (2015) LRRK2 Pharmacological Inhibition Abates α-Synuclein Induced Neurodegeneration. The Journal of Biological Chemistry
Moehle MS, Daher JP, Hull TD, et al. (2015) The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins. Human Molecular Genetics. 24: 4250-67
Boddu R, Hull TD, Bolisetty S, et al. (2015) Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury. Human Molecular Genetics. 24: 4078-93
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