Darrell J Irvine
Affiliations: | Department of Biological Engineering | Massachusetts Institute of Technology, Cambridge, MA, United States |
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Sign in to add traineeSimon J Liang | grad student | 2019-2021 | MIT (Chemistry Tree) |
B.J. Byungji Kim | post-doc | 2019- | MIT |
Christopher M. Jewell | post-doc | 2009-2012 | MIT (Chemistry Tree) |
Gregory L. Szeto | post-doc | 2011-2015 | MIT (Microtree) |
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Publications
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Bhagchandani SH, Yang L, Maiorino L, et al. (2023) Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response. Biorxiv : the Preprint Server For Biology |
Bergaggio E, Tai WT, Aroldi A, et al. (2023) ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells. Cancer Cell |
Phung I, Rodrigues KA, Marina-Zárate E, et al. (2023) A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature Communications. 14: 7107 |
Mandal S, Melo M, Gordiichuk P, et al. (2023) WASP facilitates tumor mechanosensitivity in T lymphocytes. Biorxiv : the Preprint Server For Biology |
Truex NL, Rondon A, Rössler SL, et al. (2023) Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells. Acs Central Science. 9: 1835-1845 |
Yousefpour P, Ni K, Irvine DJ. (2023) Targeted modulation of immune cells and tissues using engineered biomaterials. Nature Reviews Bioengineering. 1: 107-124 |
Truex NL, Mohapatra S, Melo M, et al. (2023) Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. Biorxiv : the Preprint Server For Biology |
Nguyen KB, Roerden M, Copeland CJ, et al. (2023) Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression. Elife. 12 |
Mota I, Patrucco E, Mastini C, et al. (2023) ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature Cancer |
Ma L, Hostetler A, Morgan DM, et al. (2023) Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity. Cell |