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Chenglai Fu

Affiliations: 
Tianjin Medical University, China 
Area:
Circulatory system
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"Chenglai Fu"
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Solomon H. Snyder post-doc 2013- Johns Hopkins

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Publications

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Qi J, Shi L, Zhu L, et al. (2023) Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP and InsP in mammalian cells. Journal of Cardiovascular Translational Research
Qi J, Cheng W, Gao Z, et al. (2023) Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 161: 114449
Chin AC, Gao Z, Riley AM, et al. (2020) The inositol pyrophosphate 5-InsP drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α. Science Advances. 6
Rao F, Cha J, Xu J, et al. (2020) Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. Molecular Cell. 79: 702
Guha P, Tyagi R, Chowdhury S, et al. (2019) IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration. Cell Reports. 26: 2692-2703.e7
Rojas T, Cheng W, Gao Z, et al. (2019) Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2. Proceedings of the National Academy of Sciences of the United States of America
Nagpal L, Fu C, Snyder SH. (2018) Inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje-cells and motor coordination via protein 4.1N. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Fu C, Rojas T, Chin AC, et al. (2018) Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1. Scientific Reports. 8: 7039
Fu C, Tyagi R, Chin AC, et al. (2017) Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation. Circulation Research
Fu C, Xu J, Cheng W, et al. (2017) Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase. Proceedings of the National Academy of Sciences of the United States of America
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