Kevin S. Thorneloe, Ph.D.

Affiliations: 
2001 University of Calgary, Calgary, Alberta, Canada 
Area:
Molecular Biology
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Michael P. Walsh grad student 2001 University of Calgary
 (Molecular basis of vascular smooth muscle potassium channels.)
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Clouse AK, Jugus MJ, Eisennagel SH, et al. (2012) Voltage-gated Na+ channel blockers reduce functional bladder capacity in the conscious spontaneously hypertensive rat. Urology. 79: 1410.e1-6
Thorneloe KS. (2010) Ion Channels as Therapeutic Targets--CHI's Fourth Annual Conference. Idrugs : the Investigational Drugs Journal. 13: 16-9
Xu X, Gordon E, Lin Z, et al. (2009) Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells. Channels (Austin, Tex.). 3: 156-60
Ritter AM, Martin WJ, Thorneloe KS. (2009) The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction. Neuroscience Letters. 452: 28-32
Thorneloe KS, Sulpizio AC, Lin Z, et al. (2008) N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I. The Journal of Pharmacology and Experimental Therapeutics. 326: 432-42
Thorneloe KS, Knorn AM, Doetsch PE, et al. (2008) Small-conductance, Ca(2+) -activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R1737-43
Thorneloe KS, Knorn A, Doetsch PE, et al. (2007) 252: Small Conductance Calcium-Activated Potassium 2 (SK2) Channels are Required Mediators of Apamin-Sensitivity in Mouse Urinary Bladder Smooth Muscle Journal of Urology. 177: 84-84
Thorneloe KS, Nelson MT. (2005) Ion channels in smooth muscle: regulators of intracellular calcium and contractility. Canadian Journal of Physiology and Pharmacology. 83: 215-42
Thorneloe KS, Meredith AL, Knorn AM, et al. (2005) Urodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladder. American Journal of Physiology. Renal Physiology. 289: F604-10
Plane F, Johnson R, Kerr P, et al. (2005) Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter. Circulation Research. 96: 216-24
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