Darren Opland, Ph.D.

Yale University, New Haven, CT 
"Darren Opland"
Mean distance: 15.77 (cluster 30)
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Ter Horst KW, Lammers NM, Trinko R, et al. (2018) Striatal dopamine regulates systemic glucose metabolism in humans and mice. Science Translational Medicine. 10
van den Heuvel JK, Furman K, Gumbs MC, et al. (2015) Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. Biological Psychiatry. 77: 633-41
Wang L, Opland D, Tsai S, et al. (2014) Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex. Nature Medicine. 20: 484-92
Kilic G, Alvarez-Mercado AI, Zarrouki B, et al. (2014) The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes. Plos One. 9: e87941
Opland D, Sutton A, Woodworth H, et al. (2013) Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity. Molecular Metabolism. 2: 423-34
Elghazi L, Gould AP, Weiss AJ, et al. (2012) Importance of β-Catenin in glucose and energy homeostasis. Scientific Reports. 2: 693
Leinninger GM, Opland DM, Jo YH, et al. (2011) Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metabolism. 14: 313-23
Wicksteed B, Brissova M, Yan W, et al. (2010) Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 59: 3090-8
Opland DM, Leinninger GM, Myers MG. (2010) Modulation of the mesolimbic dopamine system by leptin. Brain Research. 1350: 65-70
Leshan RL, Opland DM, Louis GW, et al. (2010) Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5713-23
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