Ellen C. Dengler, P.T., Ph.D.

Affiliations: 
Physical Therapy University of Texas at El Paso, El Paso, TX, United States 
Area:
pain, spinal cord
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"Ellen Dengler"
Mean distance: 19.32 (cluster 58)
 
SNBCP

Parents

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Erin D. Milligan grad student 2007-2012 Univ. of New Mexico
 (Exploring the use of synthetic delivery platforms and small molecule adjuvants to improve the efficacy of spinal Interleukin-10 gene therapy for chronic neuropathic pain.)
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Publications

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Dengler EC, Alberti LA, Bowman BN, et al. (2014) Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain. Journal of Neuroinflammation. 11: 92
Dengler EC, Liu J, Kerwin A, et al. (2013) Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 209-24
Wilkerson JL, Gentry KR, Dengler EC, et al. (2012) Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia. Brain and Behavior. 2: 155-77
Wilkerson JL, Gentry KR, Dengler EC, et al. (2012) Intrathecal cannabilactone CB(2)R agonist, AM1710, controls pathological pain and restores basal cytokine levels. Pain. 153: 1091-106
Wilkerson J, Alberti L, Wallace J, et al. (2012) Selective cannabinoid receptor 2 (CB2R) agonist AM1710 acts independently of cannabinoid receptor 1 (CB1R) responses in neuropathic CB1R -/- mice The Journal of Pain. 13: S47
Soderquist RG, Sloane EM, Loram LC, et al. (2010) Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administration. Pharmaceutical Research. 27: 841-54
Gentry KR, Wallace JA, Dengler EC, et al. (2010) Macrophage recruitment to the spinal cord following intrathecal injection: A mechanism to enhance gene therapy as a treatment of neuropathic pain Journal of Critical Care. 25: e17-e18
Wilkerson J, Dengler E, Thakur G, et al. (2009) Administration of AM 1241, a cannabinoid 2 (CB2) receptor selective agonist, to the rodent spinal cord reverses Chronic Constriction Injury (CCI) induced allodynia The Journal of Pain. 10: S22
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