Han Xu
Affiliations: | Epigenetics and Molecular Carcinogenesis | The University of Texas MD Anderson Cancer Center |
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| Zheng C, Wei Y, Zhang P, et al. (2023) CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames. Nature Structural & Molecular Biology |
| Zhang L, He W, Fu R, et al. (2023) Guide-specific loss of efficiency and off-target reduction with Cas9 variants. Nucleic Acids Research |
| Zheng C, Wei Y, Zhang Q, et al. (2023) Multiomics analyses reveal /YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance. Science Advances. 9: eadf3984 |
| Zheng C, Wei Y, Zhang P, et al. (2023) CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer. The Journal of Clinical Investigation. 133 |
| Fu R, He W, Dou J, et al. (2022) Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity. Nature Communications. 13: 474 |
| Liao Y, Chen CH, Xiao T, et al. (2022) Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 119 |
| Sun M, Wang Y, Zheng C, et al. (2021) Systematic functional interrogation of human pseudogenes using CRISPRi. Genome Biology. 22: 240 |
| He W, Wang H, Wei Y, et al. (2021) GuidePro: A multi-source ensemble predictor for prioritizing sgRNAs in CRISPR/Cas9 protein knockouts. Bioinformatics (Oxford, England) |
| Xiao T, Li W, Wang X, et al. (2018) Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proceedings of the National Academy of Sciences of the United States of America |
| Chen CH, Xiao T, Xu H, et al. (2018) Improved design and analysis of CRISPR knockout screens. Bioinformatics (Oxford, England) |