Stuart Maudsley, PhD
Affiliations: | 1997-2000 | Lefkowitz Lab | Duke University / HHMI |
2000-2004 | Human Reproductive Sciences Unit | Medical Research Council | |
2000-2004 | Center for Reproductive Biology | University of Edinburgh, Edinburgh, Scotland, United Kingdom | |
2004-2014 | Receptor Pharmacology Unit | National Institute on Aging, Baltimore, MD, United States | |
2012-2014 | Biochemistry and Molecular Biology | Johns Hopkins Bloomberg School of Public Health | |
2012-2014 | Department of Endocrinology | Johns Hopkins University School of Medicine, Baltimore, MD, United States | |
2014- | Receptor Biology Lab | University of Antwerp, Antwerpen, Vlaanderen, Belgium |
Area:
G protein-coupled receptors, Molecular Pharmacology, Proteomics, Bioinformatics, Molecular GerontologyWebsite:
https://www.researchgate.net/profile/Stuart_MaudsleyGoogle:
"https://www.google.com/search?q=stuart+maudsley&rlz=1C1GCEU_enBE820BE821&oq=st&aqs=chrome.1.69i60j69i59l3j69i60j69i61j69i60l2.1327j0j7&sourceid=chrome&ie=UTF-8"Bio:
Stuart has been recognized as a visionary pioneer in science (both physical and biomedical) from childhood where his work was publicized on the national television program ‘The Power Game’ – a U.K. wide engineering Olympiad. Stuart has been subsequently awarded and recognized throughout his career as both an intellectual innovator and as an excellent scientist. Stuart’s primary contribution to science is in the field of receptor systems biology and pharmacotherapeutics design – within this field Stuart is one of the world’s leading young Investigators. Stuart graduated from the University of Leeds with First Class Honors in Pharmacology and was awarded the Pfizer Prize for undergraduate research. For his doctoral work Stuart was one of only 6 recipients (from a University population of 40,000) of the Universities venerated ‘Named Scholarships’, i.e. the Ackroyd, Brotherton and Brown Scholarship. After gaining his Ph.D. in Receptor Pharmacology, he was then awarded a Howard Hughes Medical Institute Fellowship Award to train with Professor Robert Lefkowitz (2012 Nobel Laureate in Chemistry) at Duke University. Following this fellowship Stuart was instantly recruited to be Principal Investigator of the Receptor Biology Section at the Medical Research Council (MRC) - Human Reproductive Sciences Unit at the University of Edinburgh. During his time at the MRC his drug discovery and development abilities was implicit in his recruitment as a scientific advisor to Ardana Bioscience Inc. where he subsequently developed a novel prostate cancer therapeutic. To broaden his already considerable biomedical experience Stuart then accepted the position of Head of the Receptor Pharmacology Unit at the National Institutes of Health (NIH-National Institute on Aging) at the Johns Hopkins University Medical Center. In his time at the NIH Stuart was recognized as a ‘Scientist of Extraordinary Ability’ by the U.S. Government Naturalization services through his award of the highest level of employment recognition, i.e. EB1A visa award. In addition, while at the NIH Stuart was the recipient of multiple NIH ‘On-the-Spot’ Excellence Awards, co-recipient of the 2011 Obesity National Best practice award as well as a recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award (one of the few awards available at the NIH) for his work on neurotrophin receptor functionality in rare disorders. Upon starting a new family, and returning to Europe, Stuart continued his rigorous scientific training with his award of the highly-prized and exclusive Odysseus Program Grant. It is clear from his diverse, intense and excellent track record that he is a unique, groundbreaking and thought-provoking young scientist.
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Parents
Sign in to add mentorDan Donnelly | grad student | 1995-1996 | University of Leeds, UK (Computational Biology Tree) |
Robert J. Lefkowitz | post-doc | Duke |
Children
Sign in to add traineePublications
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Hendrickx JO, van Gastel J, Leysen H, et al. (2020) High-dimensionality Data Analysis of Pharmacological Systems Associated with Complex Diseases. Pharmacological Reviews. 72: 191-217 |
Santos-Otte P, Leysen H, van Gastel J, et al. (2019) G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence. Computational and Structural Biotechnology Journal. 17: 1265-1277 |
van Gastel J, Leysen H, Santos-Otte P, et al. (2019) The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. Aging. 11 |
Van Gastel J, Cai H, Cong WN, et al. (2019) Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. Mechanisms of Ageing and Development. 111150 |
van Gastel J, Hendrickx JO, Leysen H, et al. (2019) Enhanced Molecular Appreciation of Psychiatric Disorders Through High-Dimensionality Data Acquisition and Analytics. Methods in Molecular Biology (Clifton, N.J.). 2011: 671-723 |
Hendrickx JO, van Gastel J, Leysen H, et al. (2018) GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders. Frontiers in Pharmacology. 9: 1484 |
van Gastel J, Hendrickx JO, Leysen H, et al. (2018) β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders. Frontiers in Pharmacology. 9: 1369 |
Anckaerts C, van Gastel J, Leysen V, et al. (2018) Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality. Neurobiology of Aging. 74: 77-89 |
Leysen H, van Gastel J, Hendrickx JO, et al. (2018) G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes. International Journal of Molecular Sciences. 19 |
van Gastel J, Boddaert J, Jushaj A, et al. (2018) GIT2-a keystone in ageing and age-related disease. Ageing Research Reviews |