Emil Chris Muly, MD, PhD

Psychiatry Emory University, Atlanta, GA 
Electron Microscopy
"chris muly"

Dr. Muly has a longstanding interest in schizophrenia and is pursuing research aimed at increasing our understanding of this illness and its treatment. This includes preclinical studies of antipsychotic drug metabolism and binding within the brain, as well as participating in a large, multi-site VA study on the genetics of schizophrenia and bipolar disorder.

Recently, Dr. Muly has been engaging in research to understand how stress produces long lasting changes in behavior by altering the machinery of neural communication. By determining how stress changes the localization of key signaling molecules in a rat model of uncontrollable stress he is seeking to shed light on how stress can induce pathological behavioral states in humans.

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Mean distance: 14.49 (cluster 17)
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Zhang X, Tong F, Li CX, et al. (2015) Temporal evolution of ischemic lesions in nonhuman primates: a diffusion and perfusion MRI study. Plos One. 10: e0117290
Hubert GW, Muly EC. (2014) Distribution of AMPA receptor subunit glur1 in the bed nucleus of the stria terminalis and effect of stress. Synapse (New York, N.Y.). 68: 194-201
Muly EC, Khan ZU. (2014) Preface. Molecular basis of memory. Progress in Molecular Biology and Translational Science. 122: xv
Khan ZU, Martín-Montañez E, Navarro-Lobato I, et al. (2014) Memory deficits in aging and neurological diseases. Progress in Molecular Biology and Translational Science. 122: 1-29
Rainnie DG, Hazra R, Dabrowska J, et al. (2014) Distribution and functional expression of Kv4 family α subunits and associated KChIP β subunits in the bed nucleus of the stria terminalis. The Journal of Comparative Neurology. 522: 609-25
Hubert GW, Li C, Rainnie DG, et al. (2014) Effects of stress on AMPA receptor distribution and function in the basolateral amygdala. Brain Structure & Function. 219: 1169-79
Tremblay MÈ, Marker DF, Puccini JM, et al. (2013) Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system. Communicative & Integrative Biology. 6: e27670
Khan ZU, Martin-Montañez E, Muly EC. (2013) Schizophrenia: causes and treatments. Current Pharmaceutical Design. 19: 6451-61
Muly EC, Votaw JR, Ritchie J, et al. (2012) Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone. The Journal of Pharmacology and Experimental Therapeutics. 341: 81-9
Guo JD, Hazra R, Dabrowska J, et al. (2012) Presynaptic muscarinic M(2) receptors modulate glutamatergic transmission in the bed nucleus of the stria terminalis. Neuropharmacology. 62: 1671-83
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