Kelvin Luk
Affiliations: | McGill University, Montreal, QC, Canada |
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| Boyd SL, Kuhn NC, Patterson JR, et al. (2023) Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice. Toxicological Sciences : An Official Journal of the Society of Toxicology |
| Steinkellner T, Conrad WS, Kovacs I, et al. (2021) Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease. Brain : a Journal of Neurology |
| Wu Q, Shaikh MA, Meymand ES, et al. (2020) Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo. Acta Neuropathologica |
| Chmielarz P, Er Ş, Konovalova J, et al. (2020) GDNF/RET Signaling Pathway Activation Eliminates Lewy Body Pathology in Midbrain Dopamine Neurons. Movement Disorders : Official Journal of the Movement Disorder Society |
| Hoban DB, Shrigley S, Mattsson B, et al. (2020) Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD. Proceedings of the National Academy of Sciences of the United States of America |
| Wong YC, Luk K, Purtell K, et al. (2019) Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals? Movement Disorders : Official Journal of the Movement Disorder Society |
| Luk KC. (2019) Oxidative stress and α-synuclein conspire in vulnerable neurons to promote Parkinson's disease progression. The Journal of Clinical Investigation. 130 |
| Luna E, Decker SC, Riddle DM, et al. (2018) Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity. Acta Neuropathologica |
| Tapias V, Hu X, Luk KC, et al. (2017) Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production. Cellular and Molecular Life Sciences : Cmls |
| Osterberg VR, Spinelli KJ, Weston LJ, et al. (2015) Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism. Cell Reports. 10: 1252-60 |