Hiroshi Ichinose

Affiliations: 
Department of Life Science Tokyo Institute of Technology 
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"Hiroshi Ichinose"
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Takeshita N, Kawade N, Suzuki W, et al. (2019) Deficiency of ascorbic acid decreases the contents of tetrahydrobiopterin in the liver and the brain of ODS rats. Neuroscience Letters. 715: 134656
Miramontes-Gonzalez JP, Hightower M, Zhang K, et al. (2019) A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. Scientific Reports. 9: 5055
Kurosaki H, Yamaguchi K, Man-Yoshi K, et al. (2019) Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP. Neurochemistry International. 125: 16-24
Nagatsu T, Nakashima A, Ichinose H, et al. (2018) Human tyrosine hydroxylase in Parkinson's disease and in related disorders. Journal of Neural Transmission (Vienna, Austria : 1996)
Ishikawa T, Imamura K, Kondo T, et al. (2016) Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders. Human Molecular Genetics
Kawahata I, Ohtaku S, Tomioka Y, et al. (2015) Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system. Biochemical and Biophysical Research Communications. 465: 53-8
Horiguchi M, Ohi K, Hashimoto R, et al. (2014) Functional polymorphism (C-824T) of the tyrosine hydroxylase gene affects IQ in schizophrenia. Psychiatry and Clinical Neurosciences. 68: 456-62
Liang Y, Inagaki H, Hao Q, et al. (2013) Identification of an enhancer region for immune activation in the human GTP cyclohydrolase I gene. Biochemical and Biophysical Research Communications. 442: 72-8
Armata IA, Balaj L, Kuster JK, et al. (2013) Dopa-responsive dystonia: functional analysis of single nucleotide substitutions within the 5' untranslated GCH1 region. Plos One. 8: e76975
Hwu WL, Lee NC, Chien YH, et al. (2013) AADC deficiency: occurring in humans, modeled in rodents. Advances in Pharmacology (San Diego, Calif.). 68: 273-84
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