Nicolò Scalacci

Affiliations: 
2013-2017 Institute of Pharmaceutical Science King's College London, London, UK 
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"Nicolò Scalacci"
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Touitou M, Manetti F, Ribeiro CM, et al. (2020) Improving the Potency of -Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria. Acs Medicinal Chemistry Letters. 11: 638-644
Lauder K, Toscani A, Scalacci N, et al. (2017) Synthesis and Reactivity of Propargylamines in Organic Chemistry. Chemical Reviews. 117: 14091-14200
Scalacci N, Black GW, Mattedi G, et al. (2017) Unveiling the Biocatalytic Aromatizing Activity of Monoamine Oxidases MAO-N and 6-HDNO: Development of Chemoenzymatic Cascades for the Synthesis of Pyrroles Acs Catalysis. 7: 1295-1300
Scalacci N, Brown AK, Pavan FR, et al. (2016) Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis. European Journal of Medicinal Chemistry. 127: 147-158
Bhakta S, Scalacci N, Maitra A, et al. (2016) Design and synthesis of 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine (SQ109) pyrrole hybrid derivatives: discovery of potent anti-tubercular agents effective against multi-drug resistant mycobacteria. Journal of Medicinal Chemistry
Castagnolo D, Scalacci N, Pelloja C, et al. (2016) Microwave-Assisted Domino Reactions of Propargylamines with Isothiocyanates: Selective Synthesis of 2-Aminothiazoles and 2-Amino-4-methylenethiazolines Synlett. 27: 1883-1887
Tassini S, Castagnolo D, Scalacci N, et al. (2016) A multicomponent pharmacophore fragment-decoration approach to identify selective LRRK2-targeting probes Medchemcomm. 7: 484-494
Vincetti P, Brianza A, Scalacci N, et al. (2016) A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides Tetrahedron Letters. 57: 1464-1467
Magri A, Reilly R, Scalacci N, et al. (2015) Rethinking the old antiviral drug moroxydine: Discovery of novel analogues as anti-hepatitis C virus (HCV) agents. Bioorganic & Medicinal Chemistry Letters. 25: 5372-6
Chachignon H, Scalacci N, Petricci E, et al. (2015) Synthesis of 1,2,3-Substituted Pyrroles from Propargylamines via a One-Pot Tandem Enyne Cross Metathesis-Cyclization Reaction. The Journal of Organic Chemistry. 80: 5287-95
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