Frederic Kavaler, MD

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(1926 - 1998)
https://books.google.com/books?id=mOY1AAAAIAAJ
The researches of Dr. L. B. Flexner and his associates have previously shown that significant morphological and biochemical changes, accompanying the development of formative cells of nervous tissue (neuroblasts) into definite nerve cells (neurones), occur in the guinea pig cortex from the 41st to the 45th day of gestation (i.e. from 25 to 21 days before birth). The present study shows that evidences of functional activity, as revealed by the onset of rhythmic electrical changes, follow immediately upon this critical period of structural and chemical differentiation. There is some evidence that the appearance of cortical electrical activity depends upon a change in the membrane of the immature neurone which greatly increases its permeability to sodium. Directly related to the foregoing study is an investigation by Dr. Victor M. Kimel and Dr. Frederick Kavaler, who at the time of their work were students of Johns Hopkins
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Mean distance: 21 (cluster 28)