Cristian Alberto Lasagna-Reeves, Ph.D

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2017- Anatomy and Cell Biology Indiana University School of Medicine, Indianapolis, IN, United States 
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"Cristian Lasagna-Reeves"
Mean distance: 16.34 (cluster 11)
 
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Publications

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Puntambekar SS, Moutinho M, Lin PB, et al. (2022) CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease. Molecular Neurodegeneration. 17: 47
Taylor X, Cisternas P, Jury N, et al. (2022) Activated endothelial cells induce a distinct type of astrocytic reactivity. Communications Biology. 5: 282
Moutinho M, Puntambekar SS, Tsai AP, et al. (2022) The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease. Science Translational Medicine. 14: eabl7634
Patel H, Martinez P, Perkins A, et al. (2021) Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy. Neurobiology of Aging. 109: 52-63
Cisternas P, Taylor X, Perkins A, et al. (2020) Vascular amyloid accumulation alters the gabaergic synapse and induces hyperactivity in a model of cerebral amyloid angiopathy. Aging Cell. e13233
Taylor X, Cisternas P, You Y, et al. (2020) A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy. Journal of Neuroinflammation. 17: 223
You Y, Perkins A, Cisternas P, et al. (2019) Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy. Acta Neuropathologica Communications. 7: 26
Bemiller SM, McCray TJ, Allan K, et al. (2017) TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy. Molecular Neurodegeneration. 12: 74
Rousseaux MW, de Haro M, Lasagna-Reeves CA, et al. (2016) TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau. Elife. 5
Lasagna-Reeves CA, de Haro M, Hao S, et al. (2016) Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model. Neuron
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