Mercedes Tome

Affiliations: 
Biomedicine University of Basel, Basel, Basel-Stadt, Switzerland 
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"Mercedes Tome"
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Zarzuela L, Durán RV, Tomé M. (2023) Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance. Molecular Oncology
Gómez-Marín E, Posavec-Marjanović M, Zarzuela L, et al. (2022) The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways. Nucleic Acids Research. 50: 9838-9857
Bodineau C, Tomé M, Courtois S, et al. (2021) Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Nature Communications. 12: 4814
Nguyen TL, Nokin MJ, Terés S, et al. (2020) Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia. Molecular Oncology
Soulet F, Bodineau C, Hooks KB, et al. (2020) Furin-cleaved ELA/Apela precursor displays tumor suppressor function in renal cell carcinoma through mTORC1 activation. Jci Insight
Tomé M, Pappalardo A, Soulet F, et al. (2019) Inactivation of proprotein convertases in T cells inhibits PD-1 expression and creates a favorable immune microenvironment in colorectal cancer. Cancer Research
Tomé M, Tchorz J, Gassmann M, et al. (2019) Constitutive activation of Notch2 signalling confers chemoresistance to neural stem cells via transactivation of fibroblast growth factor receptor-1. Stem Cell Research. 35: 101390
Nguyen TL, Nokin MJ, Egorov M, et al. (2018) mTOR inhibition via displacement of phosphatidic acid induces enhanced cytotoxicity specifically in cancer cells. Cancer Research
Giachino C, Barz M, Tchorz JS, et al. (2014) GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors. Development (Cambridge, England). 141: 83-90
Toft A, Tome M, Barnett SC, et al. (2013) A comparative study of glial and non-neural cell properties for transplant-mediated repair of the injured spinal cord Glia. 61: 513-528
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