Thorsten Fritzius
Affiliations: | Biomedicine | University of Basel, Basel, Basel-Stadt, Switzerland |
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| Früh S, Boudkkazi S, Koppensteiner P, et al. (2024) Monoallelic de novo loss-of-function variants disrupt trans-synaptic control of neurotransmitter release. Science Advances. 10: eadk5462 |
| Trovò L, Kouvaros S, Schwenk J, et al. (2024) Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles. Embo Reports |
| Fritzius T, Tureček R, Fernandez-Fernandez D, et al. (2024) Preassembly of specific Gβγ subunits at GABA receptors through auxiliary KCTD proteins accelerates channel gating. Biochemical Pharmacology. 116176 |
| Rem PD, Sereikaite V, Fernández-Fernández D, et al. (2023) Soluble amyloid-β precursor peptide does not regulate GABA receptor activity. Elife. 12 |
| Bhandari P, Vandael D, Fernández-Fernández D, et al. (2021) GABA receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals. Elife. 10 |
| Werthmann RC, Tzouros M, Lamerz J, et al. (2020) Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors. Neuropharmacology. 108426 |
| Fritzius T, Stawarski M, Isogai S, et al. (2020) Structural Basis of GABA Receptor Regulation and Signaling. Current Topics in Behavioral Neurosciences |
| Sereikaite V, Fritzius T, Kasaragod V, et al. (2019) Targeting the γ-aminobutyric acid type B (GABAB) receptor complex: Development of inhibitors targeting the K+ channel tetramerization domain (KCTD) containing proteins/GABAB receptor protein-protein interaction. Journal of Medicinal Chemistry |
| Fritzius T, Bettler B. (2019) The organizing principle of GABA receptor complexes: Physiological and pharmacological implications. Basic & Clinical Pharmacology & Toxicology |
| Dinamarca MC, Raveh A, Schneider A, et al. (2019) Complex formation of APP with GABA receptors links axonal trafficking to amyloidogenic processing. Nature Communications. 10: 1331 |