Manuela Bartolini
Affiliations: | Department of Pharmacy and Biotechnology | University of Bologna |
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Publications
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Basagni F, Ortega JA, Bertozzi SM, et al. (2023) Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties. European Journal of Medicinal Chemistry. 261: 115803 |
Uliassi E, Bergamini C, Rizzardi N, et al. (2023) Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease. Bioorganic & Medicinal Chemistry. 91: 117419 |
Gandini A, Gonçalves AE, Strocchi S, et al. (2022) Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Model of Alzheimer's Disease. Acs Chemical Neuroscience. 13: 3314-3329 |
Basagni F, Naldi M, Ginex T, et al. (2022) Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads. Acs Medicinal Chemistry Letters. 13: 1812-1818 |
Bisi A, Feoli A, Trezza A, et al. (2022) Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts. Bioorganic Chemistry. 129: 106152 |
Codony S, Pont C, Griñán-Ferré C, et al. (2022) Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. 65: 4909-4925 |
Pont C, Ginex T, Griñán-Ferré C, et al. (2021) From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects. European Journal of Medicinal Chemistry. 225: 113779 |
de Andrade Ramos G, Souza de Oliveira A, Bartolini M, et al. (2021) Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties. Rsc Medicinal Chemistry. 12: 1154-1163 |
Montanari S, Allarà M, Scalvini L, et al. (2021) New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators. Molecules (Basel, Switzerland). 26 |
Tedesco D, Maj M, Malarczyk P, et al. (2021) Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines. Biochimica Et Biophysica Acta. Biomembranes. 183641 |