Manuela Bartolini

Department of Pharmacy and Biotechnology University of Bologna 
"Manuela Bartolini"
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Bayraktar G, Bartolini M, Bolognesi ML, et al. (2024) Novel multifunctional tacrine-donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies. Archiv Der Pharmazie. e2300575
Basagni F, Ortega JA, Bertozzi SM, et al. (2023) Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties. European Journal of Medicinal Chemistry. 261: 115803
Uliassi E, Bergamini C, Rizzardi N, et al. (2023) Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease. Bioorganic & Medicinal Chemistry. 91: 117419
Gandini A, Gonçalves AE, Strocchi S, et al. (2022) Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Model of Alzheimer's Disease. Acs Chemical Neuroscience. 13: 3314-3329
Basagni F, Naldi M, Ginex T, et al. (2022) Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads. Acs Medicinal Chemistry Letters. 13: 1812-1818
Bisi A, Feoli A, Trezza A, et al. (2022) Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts. Bioorganic Chemistry. 129: 106152
Codony S, Pont C, Griñán-Ferré C, et al. (2022) Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. 65: 4909-4925
Pont C, Ginex T, Griñán-Ferré C, et al. (2021) From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects. European Journal of Medicinal Chemistry. 225: 113779
de Andrade Ramos G, Souza de Oliveira A, Bartolini M, et al. (2021) Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties. Rsc Medicinal Chemistry. 12: 1154-1163
Montanari S, Allarà M, Scalvini L, et al. (2021) New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators. Molecules (Basel, Switzerland). 26
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