Pamela S. Lagali, B.Sc., M.Sc., Ph.D.

Affiliations: 
Regenerative Medicine Ottawa Hospital Research Institute/University of Ottawa 
Area:
visual system, retinal degeneration
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"Pamela Lagali"
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Publications

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Lagali PS, Shanmugalingam U, Baker AN, et al. (2023) Assessment of the uniform field electroretinogram for mouse retinal ganglion cell functional analysis. Documenta Ophthalmologica. Advances in Ophthalmology
Lagali PS, Y H Zhao B, Yan K, et al. (2020) Sensory experience modulates Atrx-mediated neuronal integrity in the mouse retina. Neuroscience
Wassmer SJ, De Repentigny Y, Sheppard D, et al. (2020) XIAP Protects Retinal Ganglion Cells in the Mutant ND4 Mouse Model of Leber Hereditary Optic Neuropathy. Investigative Ophthalmology & Visual Science. 61: 49
Lagali PS, Medina CF, Zhao BY, et al. (2016) Retinal interneuron survival requires non-cell-autonomous Atrx activity. Human Molecular Genetics. 25: 4787-4803
Lagali PS, Medina CF, Zhao BY, et al. (2016) Retinal interneuron survival requires non-cell-autonomous Atrx activity. Human Molecular Genetics
Ringuette R, Atkins M, Lagali PS, et al. (2016) A notch-Gli2 axis sustains hedgehog responsiveness of neural progenitors and Müller glia. Developmental Biology
Cronin T, Vandenberghe LH, Hantz P, et al. (2014) Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter. Embo Molecular Medicine. 6: 1175-90
McNeill B, Mazerolle C, Bassett EA, et al. (2013) Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal. Human Molecular Genetics. 22: 1005-16
Boldogkoi Z, Balint K, Awatramani GB, et al. (2009) Genetically timed, activity-sensor and rainbow transsynaptic viral tools. Nature Methods. 6: 127-30
Lagali PS, Balya D, Awatramani GB, et al. (2008) Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature Neuroscience. 11: 667-75
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